Therapeutical Class：Fluoroquinolones, inhibition of DNA gyrase and topoisomerase IV

Indication：Respiratory tract infections (acute bacterial sinusitis, community acquired pneumonia) skin and soft tissue infections, complicated abdomen infections.

Administraton：PO, IV.

Adulats: 400 mg qd for 5-14 days depending on the specific infection.

Adverse Effect：Nausea, diarrhea (1-10%), vomiting, abdominal pain, dyspepsia, dizziness (1-10%), headache (<1%), abnormal liver function test, QT interval prolongation, photosensitivity (<1%), tendon inflammation (<1%).

Contraindication：Pregnancy, children, growing adolescents, hypersensitivity to other quinolones, concurrent use of dronedarone, ziprasidone.

Pregnancy Risk：C

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