Tigecycline(Tygacil)

最後更新日期:112-12-04

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Therapeutical Class:Glycylcycline derivative, inhibits bacterial protein synthesis by binding with the 30S ribosomal subunits

Indication:Complicated infection of skin and/or subcutaneous tissue, complicated infectious disease of abdomen, community acquired pneumonia.

Administraton:IV.

Adults: 100 mg followed by 50 mg q12h for 5-14 days.

Hepatic impairment: Severe hepatic impairment (Child-Pugh class C): 100 mg followed by 25 mg q12h.

Adverse Effect:Nausea (25-30%), vomiting (>10%), diarrhea (>10%), dizziness (1-10%), acute pancretitis, fever, abdominal pain, thrombocytosis, tooth discoloration (<1%), photosensitivity (<1%).

Pregnancy Risk:D

Supply:Tygacil XE “Tygacil” 500mg Lyophilized powder Inj(老虎黴素 輝瑞)<10644>