Therapeutical Class：Quinolones, inhibition of DNA gyrase and prevention of DNA replication

Indication：Acute or chronic urinary tract or GI tract infections caused by G(-) bacteria.

Administraton：PO

Adult: 1g 4 times daily for 2 wks, then suppressive therapy of 500 mg 4 times daily. Renal impairment: Ccr <20 ml/min, half the dose.

Adverse Effect：Headache, drowsiness, confusion, mental depression, nausea, vomiting, rash, urticaria, eosinophilia, hemolytic anemia, seizures, SLE, photosensitivity, fever & reversible subjective visual disturbances.

Contraindication：Concomitant use with melphalan or other related chemotherapeutic alkylating agent, infants <3 months, prior convulsive disorders, porphyria.

Pregnancy Risk：C

Supply：Urintestin XE “Urintestin” Tab 500mg（優寧錠 榮民）＜00840＞