Therapeutical Class：Fluoroquinolones, inhibition of DNA gyrase and prevention of DNA replication

Indication：Acute exacerbations of chronic bronchitis, community acquired pneumonia.

Administraton：

Adults: PO. Acute exacerbations of chronic bronchitis: 320 mg qd for 5 days. Community acquired pneumonia: 320 mg qd for 5-7 days.

Renal impairment: CrCl <40 mL/min, HD or CAPD, 160 mg qd.

Adverse Effect：Nausea, diarrhea (1-10%), rash (1-10%), vomiting, abdominal pain, tendon inflammation (<1%), photosensitivity (<1%), dizziness, headache (1-10%), increase liver enzymes.

Pregnancy Risk：C

Supply：Factive XE “Factive” Tab 320mg（捷立復錠 聯亞生技）＜10670＞