Therapeutical Class：Macrolides, inhibit protein synthesis by binding to 50S ribosomal subunits

Indication：G(+), esp. staph and diphtheria; M. pneumoniae; Bacteroids; Leginoella pneumophila; Mycobacterium fortuitum; Chlamydia trachomatis; Campylobacter jejuni; B. pertussis, H. pylori.

Administraton：PO.

Adults: 250-500 mg q12h (FC tab) or 1000 mg qd (XL tab).

H. pylori eradication: 500 mg q12h for 7-14 days.

Children: 7.5 mg/kg q12h (FC tab).

Renal impaiment: Ccr<30 ml/min, half the dose.

Adverse Effect：Diarrhea (1-10%), nausea, abnormal taste, dyspepsia, allergy (rash,etc.) (1-10%), increased BUN (1-10%), abdominal pain, headache (1-10%).

Contraindication：Concurrent use of dronedarone, pimozide, astemizole, cisapride, terfenadine.

Pregnancy Risk：C

Supply：Klaricid XE “Klaricid” FC Tab 500mg（開羅理黴素膜衣錠 亞培）＜20075＞